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Antiproliferative Effect and the Isolated Compounds of Pouzolzia indica
Joint Authors
Kummalue, Tanawan
Sangsuwon, Chanyapat
U-pratya, Yaowalak
Jiratchariyakul, Weena
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-05-09
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Previous report showed the high potent antiproliferative effect of the methanolic part extracted from the aerial parts of Pouzolzia indica on NB4 and HT93A acute leukemic cell lines with the IC50 values of 28.5 and 49.8 μg/mL, respectively.
The bioassay-guided fractionation of the methanolic part gave 5 fractions, that is, FFI–FFV.
FFII, FFIII, and FFIV inhibited the above leukemic cell lines with the IC50 values of 15.1 (FFII), 14.4 (FFIII), 32.1 (FFIV), and 31.0 (FFII), 9.7 (FFIII), 10.5 (FFIV) μg/mL, respectively.
The compounds in these fractions were isolated using chromatographic technique.
FFII contained friedelin 1, 28-hydroxy-3-friedelanone 2, and 7-methoxy-coumarin 3.
FFIII contained 6, 7-dimethoxy-coumarin 4, scopoletin 5, methyl caffeate 6.
FFIV contained sitosteryl glucoside 7 and a supposed glycosphingolipid 8.
The chemical structures were elucidated by spectroscopic methods.
American Psychological Association (APA)
Sangsuwon, Chanyapat& Jiratchariyakul, Weena& U-pratya, Yaowalak& Kummalue, Tanawan. 2013. Antiproliferative Effect and the Isolated Compounds of Pouzolzia indica. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-464311
Modern Language Association (MLA)
Sangsuwon, Chanyapat…[et al.]. Antiproliferative Effect and the Isolated Compounds of Pouzolzia indica. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-464311
American Medical Association (AMA)
Sangsuwon, Chanyapat& Jiratchariyakul, Weena& U-pratya, Yaowalak& Kummalue, Tanawan. Antiproliferative Effect and the Isolated Compounds of Pouzolzia indica. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-464311
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-464311