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Regulatory T Cells in Human Ovarian Cancer
Joint Authors
Zou, Weiping
Liu, Rebecca
Peng, Dong-Jun
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-06
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Multiple layers of suppressive components including regulatory T (TReg) cells, suppressive antigen-presenting cells, and inhibitory cytokines form suppressive networks in the ovarian cancer microenvironment.
It has been demonstrated that as a major suppressive element, TReg cells infiltrate tumor, interact with several types of immune cells, and mediate immune suppression through different molecular and cellular mechanisms.
In this paper, we focus on human ovarian cancer and will discuss the nature of TReg cells including their subsets, trafficking, expansion, and function.
We will briefly review the development of manipulation of TReg cells in preclinical and clinical settings.
American Psychological Association (APA)
Peng, Dong-Jun& Liu, Rebecca& Zou, Weiping. 2012. Regulatory T Cells in Human Ovarian Cancer. Journal of Oncology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-464455
Modern Language Association (MLA)
Peng, Dong-Jun…[et al.]. Regulatory T Cells in Human Ovarian Cancer. Journal of Oncology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-464455
American Medical Association (AMA)
Peng, Dong-Jun& Liu, Rebecca& Zou, Weiping. Regulatory T Cells in Human Ovarian Cancer. Journal of Oncology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-464455
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-464455