Impact of the Body Mass on Complications and Outcome in Multiple Trauma Patients : What Does the Weight Weigh?
Joint Authors
Mommsen, Philipp
Andruszkow, Hagen
Hildebrand, Frank
Zeckey, Christian
Veh, Juliane
Frink, Michael
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-08-19
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Obesity is known as an independent risk factor for various morbidities.
The influence of an increased body mass index (BMI) on morbidity and mortality in critically injured patients has been investigated with conflicting results.
To verify the impact of weight disorders in multiple traumatized patients, 586 patients with an injury severity score >16 points treated at a level I trauma center between 2005 and 2011 were differentiated according to the BMI and analyzed regarding morbidity and outcome.
Plasma levels of interleukin- (IL-) 6 and C-reactive protein (CRP) were measured during clinical course to evaluate the inflammatory response to the “double hit” of weight disorders and multiple trauma.
In brief, obesity was the highest risk factor for development of a multiple organ dysfunction syndrome (MODS) (OR 4.209, 95%-CI 1.515–11.692) besides injury severity (OR 1.054, 95%-CI 1.020–1.089) and APACHE II score (OR 1.059, 95%-CI 1.001–1.121).
In obese patients as compared to those with overweight, normal weight, and underweight, the highest levels of CRP were continuously present while increased systemic IL-6 levels were found until day 4.
In conclusion, an altered posttraumatic inflammatory response in obese patients seems to determine the risk for multiple organ failure after severe trauma.
American Psychological Association (APA)
Andruszkow, Hagen& Veh, Juliane& Mommsen, Philipp& Zeckey, Christian& Hildebrand, Frank& Frink, Michael. 2013. Impact of the Body Mass on Complications and Outcome in Multiple Trauma Patients : What Does the Weight Weigh?. Mediators of Inflammation،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-464492
Modern Language Association (MLA)
Andruszkow, Hagen…[et al.]. Impact of the Body Mass on Complications and Outcome in Multiple Trauma Patients : What Does the Weight Weigh?. Mediators of Inflammation No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-464492
American Medical Association (AMA)
Andruszkow, Hagen& Veh, Juliane& Mommsen, Philipp& Zeckey, Christian& Hildebrand, Frank& Frink, Michael. Impact of the Body Mass on Complications and Outcome in Multiple Trauma Patients : What Does the Weight Weigh?. Mediators of Inflammation. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-464492
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-464492