Diabetes Insipidus as a Complication of Wegener's Granulomatosis and Its Treatment with Biologic Agents
Joint Authors
Cunnington, Joanna Rosalind
Jois, Ramesh
Zammit, Ivan
Scott, David
Isaacs, John
Source
International Journal of Rheumatology
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-07-26
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Wegener's granulomatosis of the pituitary gland resulting in diabetes insipidus is a rare complication of the disease.
Standard treatment for Wegener's granulomatosis involves a combination of prednisolone and cylophosphamide, however biologic agents are now being used in refractory cases.
We report three cases of patients with diabetes insipidus as a complication of Wegener's granulomatosis who were treated with biologic agents.
All three cases showed clinical response to treatment with biologic agents including rituximab and alemtuzumab and two cases demonstrated improvement in pituitary gland abnormalities by MRI.
Clinicians should be aware that diabetes insipidus can present as a complication of Wegener's granulomatosis and that biologic therapies may be effective in refractory cases.
American Psychological Association (APA)
Cunnington, Joanna Rosalind& Jois, Ramesh& Zammit, Ivan& Scott, David& Isaacs, John. 2009. Diabetes Insipidus as a Complication of Wegener's Granulomatosis and Its Treatment with Biologic Agents. International Journal of Rheumatology،Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-464535
Modern Language Association (MLA)
Cunnington, Joanna Rosalind…[et al.]. Diabetes Insipidus as a Complication of Wegener's Granulomatosis and Its Treatment with Biologic Agents. International Journal of Rheumatology No. 2009 (2009), pp.1-4.
https://search.emarefa.net/detail/BIM-464535
American Medical Association (AMA)
Cunnington, Joanna Rosalind& Jois, Ramesh& Zammit, Ivan& Scott, David& Isaacs, John. Diabetes Insipidus as a Complication of Wegener's Granulomatosis and Its Treatment with Biologic Agents. International Journal of Rheumatology. 2009. Vol. 2009, no. 2009, pp.1-4.
https://search.emarefa.net/detail/BIM-464535
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-464535