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Open Randomized Clinical Trial on JWSJZ Decoction for the Treatment of ALS Patients
Joint Authors
Bao, Jie
Zhou, Hua
Yu, Li
Wang, Jun
Cai, Ding-Fang
Su, Xiaojing
Pan, Weidong
Zhu, Jin
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-05
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
To investigate the efficacy and safety of the traditional Chinese medicine Jiawei Sijunzi (JWSJZ) decoction for the treatment of patients with amyotrophic lateral sclerosis (ALS).
Methods.
Forty-eight patients with ALS were divided into a JWSJZ group (n=24) and a control group (n=24) using a randomized number method.
Together with the basic treatment for ALS, JWSJZ decoction was added to the treatment regimen of patients in the JWSJZ group or Riluzole was administered to the control group for 6 months.
Neurologists evaluated the treated and control patients using the ALS functional rating scale (ALSFRS) before, 3 and 6 months after starting the additional treatments.
Results.
The ALSFRS scores in both groups were lower 3 and 6 months after treatment than before.
There was a significant difference at 6 months after treatment between the subgroups of patients with ALS whose limbs were the initial site of attack.
No serious adverse effects were observed in the JWSJZ group.
Conclusion.
JWSJZ decoction may be a safe treatment for ALS, and may have delayed the development of ALS, especially in the subgroup of patients in whom the limbs were attacked first when compared with Riluzole treatment.
American Psychological Association (APA)
Pan, Weidong& Su, Xiaojing& Bao, Jie& Wang, Jun& Zhu, Jin& Cai, Ding-Fang…[et al.]. 2013. Open Randomized Clinical Trial on JWSJZ Decoction for the Treatment of ALS Patients. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-464655
Modern Language Association (MLA)
Pan, Weidong…[et al.]. Open Randomized Clinical Trial on JWSJZ Decoction for the Treatment of ALS Patients. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-464655
American Medical Association (AMA)
Pan, Weidong& Su, Xiaojing& Bao, Jie& Wang, Jun& Zhu, Jin& Cai, Ding-Fang…[et al.]. Open Randomized Clinical Trial on JWSJZ Decoction for the Treatment of ALS Patients. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-464655
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-464655