![](/images/graphics-bg.png)
Health-Related Quality of Life in the Gender, Race, And Clinical Experience Trial
Joint Authors
Squires, Kathleen
Feinberg, Judith
Currier, Judith
Coate, Bruce
Saag, Michael
Mrus, Joseph
Ryan, Robert
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-08-28
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
We report health-related QoL (HRQoL) from GRACE (Gender, Race, And Clinical Experience) study by sex and race over 48 weeks.
Methods.
429 treatment-experienced adults (HIV-1 RNA≥1000 copies/mL) received darunavir/ritonavir 600/100 mg twice daily plus an appropriate background regimen.
QoL was measured by the Functional Assessment of HIV Infection (FAHI) questionnaire.
Results.
67% women and 77% men, including 67.4% black, 76.0% Hispanic, and 73.8% white patients, completed the trial.
Baseline total FAHI scores were similar between sexes and races.
Total FAHI of the entire population improved by Week 4 (P<.05); near-maximum changes obtained by Week 12 were maintained through Week 48.
Women and black patients demonstrated larger improvements in total FAHI versus men, and Hispanic and white patients, respectively.
Conclusion.
HRQoL improved in all sex and racial/ethnic groups.
Sex-based and race-based differences in improvements in FAHI subscales may provide insight into subtle differences of HIV-1 and treatment on HRQoL in different populations.
American Psychological Association (APA)
Feinberg, Judith& Saag, Michael& Squires, Kathleen& Currier, Judith& Ryan, Robert& Coate, Bruce…[et al.]. 2011. Health-Related Quality of Life in the Gender, Race, And Clinical Experience Trial. AIDS Research and Treatment،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-464801
Modern Language Association (MLA)
Feinberg, Judith…[et al.]. Health-Related Quality of Life in the Gender, Race, And Clinical Experience Trial. AIDS Research and Treatment No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-464801
American Medical Association (AMA)
Feinberg, Judith& Saag, Michael& Squires, Kathleen& Currier, Judith& Ryan, Robert& Coate, Bruce…[et al.]. Health-Related Quality of Life in the Gender, Race, And Clinical Experience Trial. AIDS Research and Treatment. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-464801
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-464801