A Pair of Partially Overlapping Arabidopsis Genes with Antagonistic Circadian Expression
Joint Authors
Zubko, Elena
Meyer, Peter
Kunova, Andrea
Source
International Journal of Plant Genomics
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-03
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
A large number of plant genes are aligned with partially overlapping genes in antisense orientation.
Transcription of both genes would therefore favour the formation of double-stranded RNA, providing a substrate for the RNAi machinery, and enhanced antisense transcription should therefore reduce sense transcript levels.
We have identified a gene pair that resembles a model for antisense-based gene regulation as a T-DNA insertion into the antisense gene causes a reduction in antisense transcript levels and an increase in sense transcript levels.
The same effect was, however, also observed when the two genes were inserted as transgenes into different chromosomal locations, independent of the sense and antisense gene being expressed individually or jointly.
Our results therefore indicate that antagonistic changes in sense/antisense transcript levels do not necessarily reflect antisense-mediated regulation.
More likely, the partial overlap of the two genes may have favoured the evolution of antagonistic expression patterns preventing RNAi effects.
American Psychological Association (APA)
Kunova, Andrea& Zubko, Elena& Meyer, Peter. 2012. A Pair of Partially Overlapping Arabidopsis Genes with Antagonistic Circadian Expression. International Journal of Plant Genomics،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-464845
Modern Language Association (MLA)
Kunova, Andrea…[et al.]. A Pair of Partially Overlapping Arabidopsis Genes with Antagonistic Circadian Expression. International Journal of Plant Genomics No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-464845
American Medical Association (AMA)
Kunova, Andrea& Zubko, Elena& Meyer, Peter. A Pair of Partially Overlapping Arabidopsis Genes with Antagonistic Circadian Expression. International Journal of Plant Genomics. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-464845
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-464845