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Modeling Airflow Using Subject-Specific 4DCT-Based Deformable Volumetric Lung Models
Joint Authors
Seyfi, Behnaz
Ilegbusi, Olusegun J.
Kupelian, Patrick
Meeks, Sanford
Santhanam, Anand P.
Min, Yugang
Li, Zhiliang
Source
International Journal of Biomedical Imaging
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-20
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Lung radiotherapy is greatly benefitted when the tumor motion caused by breathing can be modeled.
The aim of this paper is to present the importance of using anisotropic and subject-specific tissue elasticity for simulating the airflow inside the lungs.
A computational-fluid-dynamics (CFD) based approach is presented to simulate airflow inside a subject-specific deformable lung for modeling lung tumor motion and the motion of the surrounding tissues during radiotherapy.
A flow-structure interaction technique is employed that simultaneously models airflow and lung deformation.
The lung is modeled as a poroelastic medium with subject-specific anisotropic poroelastic properties on a geometry, which was reconstructed from four-dimensional computed tomography (4DCT) scan datasets of humans with lung cancer.
The results include the 3D anisotropic lung deformation for known airflow pattern inside the lungs.
The effects of anisotropy are also presented on both the spatiotemporal volumetric lung displacement and the regional lung hysteresis.
American Psychological Association (APA)
Ilegbusi, Olusegun J.& Li, Zhiliang& Seyfi, Behnaz& Min, Yugang& Meeks, Sanford& Kupelian, Patrick…[et al.]. 2012. Modeling Airflow Using Subject-Specific 4DCT-Based Deformable Volumetric Lung Models. International Journal of Biomedical Imaging،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-464955
Modern Language Association (MLA)
Ilegbusi, Olusegun J.…[et al.]. Modeling Airflow Using Subject-Specific 4DCT-Based Deformable Volumetric Lung Models. International Journal of Biomedical Imaging No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-464955
American Medical Association (AMA)
Ilegbusi, Olusegun J.& Li, Zhiliang& Seyfi, Behnaz& Min, Yugang& Meeks, Sanford& Kupelian, Patrick…[et al.]. Modeling Airflow Using Subject-Specific 4DCT-Based Deformable Volumetric Lung Models. International Journal of Biomedical Imaging. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-464955
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-464955