Nickel(II)‎ Complexes of Hydrazone of Isoniazid and Their Magneto-Spectral, Electrochemical, Thermal and Antimicrobial Investigations

Abstract EN

The synthesis of novel nickel(II) complexes with new ligand derived from hydrazone of isoniazid has been reported.

The complexes have general compositions [Ni(L)2X2] or [Ni(L)3](ClO4)2, where L = N-isonicotinamido-furfuraldimine (INH-FFL) and X=Cl− or NCS−.

The ligand hydrazone behaves as neutral bidentate (N and O donor) through the carbonyl oxygen and azomethine nitrogen.

On the basis of elemental analysis, molecular weight determinations, magnetic susceptibility/moment, thermogravimetric, electrochemical, and spectroscopic studies, the new complexes have been characterized with octahedral geometry.

The antibacterial and antifungal studies of the present complexes show that they are moderate antibacterial and antifungal agents.