Epitope Analysis of Cerebrospinal Fluid IgG in Japanese Multiple Sclerosis Patients Using Phage Display Method
Joint Authors
Sato, Shigeru
Itoyama, Yasuto
Misu, Tatsuro
Fujihara, Kazuo
Fujimori, Juichi
Nakashima, Ichiro
Source
Multiple Sclerosis International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-11-10
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
To investigate the antigen recognized by cerebrospinal fluid (CSF) high affinity IgG in patients with multiple sclerosis (MS), the phage display method was applied to the CSF from 15 MS and 10 control patients.
Peptide sequences recognized by MS and control CSF IgG were individual specific, and no common motif was found.
Peptide sequences frequently showed homology to various kinds of amino acid sequences of ubiquitous viruses such as epstein barr virus (EBV) and herpes simplex virus (HSV), although the frequency was not specific to MS patients.
MS CSF IgG may recognize various types of ubiquitous viral antigen and may be increased by a bystander response.
American Psychological Association (APA)
Fujimori, Juichi& Nakashima, Ichiro& Fujihara, Kazuo& Misu, Tatsuro& Sato, Shigeru& Itoyama, Yasuto. 2011. Epitope Analysis of Cerebrospinal Fluid IgG in Japanese Multiple Sclerosis Patients Using Phage Display Method. Multiple Sclerosis International،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-465220
Modern Language Association (MLA)
Fujimori, Juichi…[et al.]. Epitope Analysis of Cerebrospinal Fluid IgG in Japanese Multiple Sclerosis Patients Using Phage Display Method. Multiple Sclerosis International No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-465220
American Medical Association (AMA)
Fujimori, Juichi& Nakashima, Ichiro& Fujihara, Kazuo& Misu, Tatsuro& Sato, Shigeru& Itoyama, Yasuto. Epitope Analysis of Cerebrospinal Fluid IgG in Japanese Multiple Sclerosis Patients Using Phage Display Method. Multiple Sclerosis International. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-465220
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465220
