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Tangential Biopsy Thickness versus Lesion Depth in Longitudinal Melanonychia : A Pilot Study
Joint Authors
Di Chiacchio, Nilton
Loureiro, Walter Refkalefsky
Michalany, Nilceo Schwery
Kezam Gabriel, Felipe Veiga
Source
Dermatology Research and Practice
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-14
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Longitudinal melanonychia can be caused by melanocyte activation (hypermelanosis) or proliferation (lentigo, nevus or melanoma).
Histopathologic examination is mandatory for suspicious cases of melanomas.
Tangential biopsy of the matrix is an elegant technique avoiding nail plate dystrophy, but it was unknown whether the depth of the sample obtained by this method is adequate for histopathologic diagnosis.
Twenty-two patients with longitudinal melanonychia striata were submitted to tangential matrix biopsies described by Haneke.
The tissue was stained with hematoxylin-eosin and the specimens were measured at 3 distinct points according to the total thickness: largest (A), intermediate (B) and narrowest (C) then divided into 4 groups according to the histopathologic diagnosis (G1: hypermelanosis; G2: lentigos; G3: nevus; G4: melanoma).
The lesions were measured using the same method.
The mean specimen/lesion thickness measure values for each group was: G1: 0,59/0,10 mm, G2: 0,67/0,08 mm, G3: 0,52/0,05 mm, G4: 0,58/0,10 mm.
The general average thickness for all the specimens/lesions was 0,59/0,08 mm.
We concluded that the tangential excision, for longitudinal melanonychia, provides an adequate material for histopathological diagnosis.
American Psychological Association (APA)
Di Chiacchio, Nilton& Loureiro, Walter Refkalefsky& Michalany, Nilceo Schwery& Kezam Gabriel, Felipe Veiga. 2012. Tangential Biopsy Thickness versus Lesion Depth in Longitudinal Melanonychia : A Pilot Study. Dermatology Research and Practice،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-465254
Modern Language Association (MLA)
Di Chiacchio, Nilton…[et al.]. Tangential Biopsy Thickness versus Lesion Depth in Longitudinal Melanonychia : A Pilot Study. Dermatology Research and Practice No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-465254
American Medical Association (AMA)
Di Chiacchio, Nilton& Loureiro, Walter Refkalefsky& Michalany, Nilceo Schwery& Kezam Gabriel, Felipe Veiga. Tangential Biopsy Thickness versus Lesion Depth in Longitudinal Melanonychia : A Pilot Study. Dermatology Research and Practice. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-465254
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465254