Cortical Anaplastic Ependymoma with Significant Desmoplasia : A Case Report and Literature Review

Abstract EN

Ectopic brain anaplastic ependymomas with no connection to the ventricles are rare.

We present a rare case of a 25-year-old male who presented with generalized convulsions.

Computed tomography (CT), Magnetic Resonance Imaging (MRI), and magnetic resonance spectroscopy (MRS) showed characters of an intra- and extra-axial lesion.

Intraoperatively, the lesion was a cortical solid mass that had no connections to the dura or to the ventricle.

The histological diagnosis showed an anaplastic ependymoma with WHO grade III with distinctive desmoplasia.

A literature review of ectopic anaplastic ependymomas regarding their clinical presentations, management, and prognostic factors was performed.

There is a need to establish a clinically based histopathological grading system for anaplastic ependymomas.

Ectopic anaplastic ependymomas should be included in the preoperative differential diagnosis.