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Synthesis and Antioxidant Activities of Novel 5-Chlorocurcumin, Complemented by Semiempirical Calculations
Joint Authors
Kadhum, Abdul Amir H.
al-Amiery, Ahmed A.
Obayes, Hasan R.
Mohamad, Abu Bakar
Source
Bioinorganic Chemistry and Applications
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-21
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
The novel curcumin derivative (1E,4Z,6E)-5-chloro-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one (5-chlorocurcumin) was prepared from natural curcumin.
The newly synthesised compound was characterised by spectral studies (IR, 1H NMR, and 13C NMR).
The free radical scavenging activity of 5-chlorocurcumin has been determined by measuring interaction with the stable free radical DPPH, and 5-chlorocurcumin has shown encouraging antioxidant activities.
Theory calculations of the synthesised 5-chlorocurcumin were performed using molecular structures with optimised geometries.
Molecular orbital calculations provided a detailed description of the orbitals, including spatial characteristics, nodal patterns, and the contributions of individual atoms.
American Psychological Association (APA)
al-Amiery, Ahmed A.& Kadhum, Abdul Amir H.& Obayes, Hasan R.& Mohamad, Abu Bakar. 2013. Synthesis and Antioxidant Activities of Novel 5-Chlorocurcumin, Complemented by Semiempirical Calculations. Bioinorganic Chemistry and Applications،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-465360
Modern Language Association (MLA)
al-Amiery, Ahmed A.…[et al.]. Synthesis and Antioxidant Activities of Novel 5-Chlorocurcumin, Complemented by Semiempirical Calculations. Bioinorganic Chemistry and Applications No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-465360
American Medical Association (AMA)
al-Amiery, Ahmed A.& Kadhum, Abdul Amir H.& Obayes, Hasan R.& Mohamad, Abu Bakar. Synthesis and Antioxidant Activities of Novel 5-Chlorocurcumin, Complemented by Semiempirical Calculations. Bioinorganic Chemistry and Applications. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-465360
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465360