![](/images/graphics-bg.png)
Grazing Molecule Excitation as a Tool to Analyse the Amino Acid Sequence in Oligopeptides
Joint Authors
Schmidt, L.
Komarov, V. V.
Jungclas, H.
Popova, A. M.
Source
Journal of Atomic, Molecular, and Optical Physics
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
A novel mass spectrometric method to analyse the sequence of amino acid residues in oligopeptides is proposed.
Amino acid residues in peptide molecules contain chain-like structures of identical CH dipoles (IR antennas), which acquire IR energy quanta by interaction with periodic Coulomb fields and accumulate vibration excitation energy.
This can subsequently lead to the dissociation of specific trap bonds inside the peptide molecule.
Such excitation and dissociation processes are assumed to occur when peptide ions graze at atomic distance along a set of screened charges on a surface.
These processes of grazing molecule excitation (GME) and dissociation (GMD) were applied to analyse sequences of oligopeptides by using TOF mass spectrometry.
At specific grazing velocities the experimental fragment ion spectra of oligopeptides must contain a peak of high abundance corresponding to the N-terminal amino acid.
This specific property of GMD offers the possibility to determine the amino acid sequence of oligopeptides.
American Psychological Association (APA)
Jungclas, H.& Schmidt, L.& Komarov, V. V.& Popova, A. M.. 2011. Grazing Molecule Excitation as a Tool to Analyse the Amino Acid Sequence in Oligopeptides. Journal of Atomic, Molecular, and Optical Physics،Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-465434
Modern Language Association (MLA)
Jungclas, H.…[et al.]. Grazing Molecule Excitation as a Tool to Analyse the Amino Acid Sequence in Oligopeptides. Journal of Atomic, Molecular, and Optical Physics No. 2011 (2011), pp.1-6.
https://search.emarefa.net/detail/BIM-465434
American Medical Association (AMA)
Jungclas, H.& Schmidt, L.& Komarov, V. V.& Popova, A. M.. Grazing Molecule Excitation as a Tool to Analyse the Amino Acid Sequence in Oligopeptides. Journal of Atomic, Molecular, and Optical Physics. 2011. Vol. 2011, no. 2011, pp.1-6.
https://search.emarefa.net/detail/BIM-465434
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465434