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Improved Survival with the Patients with Variceal Bleed
Joint Authors
Sharma, Praveen
Sarin, Shiv Kumar
Source
International Journal of Hepatology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Variceal hemorrhage is a major cause of death in patients with cirrhosis.
Over the past two decades new treatment modalities have been introduced in the management of acute variceal bleeding (AVB) and several recent studies have suggested that the outcome of patients with cirrhosis and AVB has improved.
Improved supportive measures, combination therapy which include early use of portal pressure reducing drugs with low rates of adverse effects (somatostatin, octerotide or terlipressin) and endoscopic variceal ligation has become the first line treatment in the management of AVB.
Short-term antibiotic prophylaxis, early use of lactulose for prevention of hepatic encephalopathy, application of early transjugular intrahepatic portasystemic shunts (TIPS), fully covered self-expandable metallic stent in patients for AVB may be useful in those cases where balloon tamponade is considered.
Early and wide availability of liver transplantation has changed the armamentarium of the clinician for patients with AVB.
High hepatic venous pressure gradient (HVPG) >20 mmHg in AVB has become a useful predictor of outcomes and more aggressive therapies with early TIPS based on HVPG measurement may be the treatment of choice to reduce mortality further.
American Psychological Association (APA)
Sharma, Praveen& Sarin, Shiv Kumar. 2011. Improved Survival with the Patients with Variceal Bleed. International Journal of Hepatology،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-465464
Modern Language Association (MLA)
Sharma, Praveen& Sarin, Shiv Kumar. Improved Survival with the Patients with Variceal Bleed. International Journal of Hepatology No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-465464
American Medical Association (AMA)
Sharma, Praveen& Sarin, Shiv Kumar. Improved Survival with the Patients with Variceal Bleed. International Journal of Hepatology. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-465464
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465464