Histopathologic and Radiologic Assessment of Chemotherapeutic Response in Ewing's Sarcoma : A Review
Joint Authors
García-Castellano, José M.
Atallah Yordi, Nagib
Reyes, Carolina
Healey, John H.
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-03-01
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Ewing’s sarcoma is a highly malignant tumor that metastasizes rapidly and is thus associated with a low survival rate.
The intensification of chemotherapy has been shown to improve the overall survival of patients with Ewing’s sarcoma.
However, intensified chemotherapy can lead to increased toxicity or even the development of secondary malignancies.
The stratification of patients with Ewing’s sarcoma into “good” and “poor” responders may help guide the administration of progressively more intensified chemotherapy.
Thus, an accurate assessment of the chemotherapeutic response, as well as the extent of chemotherapy-induced tumor necrosis, is critical for avoiding potential treatment-related complications in these patients.
This paper reviews the methods currently used to evaluate chemotherapeutic response in Ewing’s sarcoma, focusing specifically on histopathologic and imaging analyses, and discusses novel therapies and imaging methods that may help improve the overall survival of these patients.
American Psychological Association (APA)
García-Castellano, José M.& Atallah Yordi, Nagib& Reyes, Carolina& Healey, John H.. 2012. Histopathologic and Radiologic Assessment of Chemotherapeutic Response in Ewing's Sarcoma : A Review. Sarcoma،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-465530
Modern Language Association (MLA)
García-Castellano, José M.…[et al.]. Histopathologic and Radiologic Assessment of Chemotherapeutic Response in Ewing's Sarcoma : A Review. Sarcoma No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-465530
American Medical Association (AMA)
García-Castellano, José M.& Atallah Yordi, Nagib& Reyes, Carolina& Healey, John H.. Histopathologic and Radiologic Assessment of Chemotherapeutic Response in Ewing's Sarcoma : A Review. Sarcoma. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-465530
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465530