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Surgical Treatment of Sporadic Pancreatic Neuroendocrine Tumors : A State of the Art Review
Joint Authors
Gladhaug, Ivar Prydz
Edwin, Bjørn
Haugvik, Sven-Petter
Labori, Knut Jørgen
Mathisen, Øystein
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-12-10
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Medicine
Information Technology and Computer Science
Abstract EN
Pancreatic neuroendocrine tumors (PNETs) are rare neoplasms.
They are clinically diverse and divided into functioning and nonfunctioning disease, depending on their ability to produce symptoms due to hormone production.
Surgical resection is the only curative treatment and remains the cornerstone therapy for this patient group, even in patients with advanced disease.
Over the last decade there has been a noticeable trend towards more aggressive surgery as well as more minimally invasive surgery in patients with PNETs.
This has resulted in improved long-term survival in patients with locally advanced and metastatic disease treated aggressively, as well as shorter hospital stays and comparable long-term outcomes in patients with limited disease treated minimally invasively.
There are still controversies related to issues of surgical treatment of PNETs, such as to what extent enucleation, lymph node sampling, and vascular reconstruction are beneficial for the oncologic outcome.
Histopathologic tumor classification is of high clinical importance for treatment planning and prognostic evaluation of patients with PNETs.
A constant challenge, which relates to the treatment of PNETs, is the lack of an internationally accepted histopathological classification system.
This paper reviews current issues on the surgical treatment of sporadic PNETs with specific focus on surgical approaches and tumor classification.
American Psychological Association (APA)
Haugvik, Sven-Petter& Labori, Knut Jørgen& Edwin, Bjørn& Mathisen, Øystein& Gladhaug, Ivar Prydz. 2012. Surgical Treatment of Sporadic Pancreatic Neuroendocrine Tumors : A State of the Art Review. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-465531
Modern Language Association (MLA)
Haugvik, Sven-Petter…[et al.]. Surgical Treatment of Sporadic Pancreatic Neuroendocrine Tumors : A State of the Art Review. The Scientific World Journal No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-465531
American Medical Association (AMA)
Haugvik, Sven-Petter& Labori, Knut Jørgen& Edwin, Bjørn& Mathisen, Øystein& Gladhaug, Ivar Prydz. Surgical Treatment of Sporadic Pancreatic Neuroendocrine Tumors : A State of the Art Review. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-465531
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465531