Lacrimal Gland Involvement in Lymphomatoid Granulomatosis and Review of the Literature
Joint Authors
Cannon, Paul S.
Dodd, Thomas
Selva, Dinesh
Pradeep, Thanuja Gopal
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-09-01
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To describe the clinicoradiological and histopathological findings in a case of lacrimal gland enlargement secondary to lymphomatoid granulomatosis (LG) and to review the literature.
Design.
Case report and systematic literature review.
Methods.
A 75-year-old woman presented with right ptosis.
Computerised tomography showed lacrimal gland enlargement, and biopsy done was inconclusive.
She subsequently developed pulmonary symptoms and underwent transbronchial biopsy that was diagnosed as LG.
Pub Med and OVID databases were searched using the term “orbit/eye involvement in lymphomatoid granulomatosis”.
Articles that predated the databases were gathered from current references.
Results.
The patient underwent lacrimal gland biopsy which revealed necrotic and inflamed tissue with no further categorisation but transbronchial biopsy helped in establishing the diagnosis of LG.
On initiation of prednisolone and cyclophosphamide, her orbital lesion resolved but the patient died following massive pulmonary hemorrhage within a month of diagnosis.
Conclusion.
Ophthalmic involvement in LG is very rare.
Varied presentations are due to central nervous system involvement, vasculitis, or infiltration of ocular or orbital structures.
LG is an angiocentric and angiodestructive granulomatous disorder and can involve any tissue, thus accounting for the variable presentations reported in literature.
American Psychological Association (APA)
Pradeep, Thanuja Gopal& Cannon, Paul S.& Dodd, Thomas& Selva, Dinesh. 2010. Lacrimal Gland Involvement in Lymphomatoid Granulomatosis and Review of the Literature. Journal of Ophthalmology،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-465584
Modern Language Association (MLA)
Pradeep, Thanuja Gopal…[et al.]. Lacrimal Gland Involvement in Lymphomatoid Granulomatosis and Review of the Literature. Journal of Ophthalmology No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-465584
American Medical Association (AMA)
Pradeep, Thanuja Gopal& Cannon, Paul S.& Dodd, Thomas& Selva, Dinesh. Lacrimal Gland Involvement in Lymphomatoid Granulomatosis and Review of the Literature. Journal of Ophthalmology. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-465584
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465584