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Cytoreductive Surgery Combined with Hyperthermic Intraperitoneal Intraoperative Chemotherapy in the Treatment of Advanced Epithelial Ovarian Cancer
Joint Authors
Kakolyris, Stylianos
Karamveri, Christina
Tentes, Antonios-Apostolos K.
Kyziridis, Dimitrios
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-09
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background/Aims.
Intraperitoneal intraoperative hyperthermic chemotherapy (HIPEC) has been used in the treatment of ovarian cancer.
The purpose of the study is to determine the efficacy of HIPEC after cytoreductive surgery in advanced ovarian cancer.
Patients/Methods.
From 2006 to 2010 patients with advanced ovarian cancer were enrolled in a prospective nonrandomized study to undergo cytoreductive surgery combined with HIPEC.
Clinical and histopathological variables were correlated to hospital mortality, morbidity, survival, and recurrences.
Results.
The mean age of 43 women was 59.9±13.8 (16–82) years.
The hospital mortality and morbidity rate were 4.7% and 51.2%, respectively.
Complete cytoreduction was possible in 69.8%.
The overall 5-year survival rate was 54%.
The prognostic indicators of survival were the extent of prior surgery (P=0.048) and the extent of peritoneal dissemination (P=0.011).
The recurrence rate was 30.2%.
Conclusions.
Maximal cytoreductive surgery combined with HIPEC is a well-tolerated, feasible, and promising method of treatment in advanced ovarian cancer.
American Psychological Association (APA)
Tentes, Antonios-Apostolos K.& Kakolyris, Stylianos& Kyziridis, Dimitrios& Karamveri, Christina. 2012. Cytoreductive Surgery Combined with Hyperthermic Intraperitoneal Intraoperative Chemotherapy in the Treatment of Advanced Epithelial Ovarian Cancer. Journal of Oncology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-465613
Modern Language Association (MLA)
Tentes, Antonios-Apostolos K.…[et al.]. Cytoreductive Surgery Combined with Hyperthermic Intraperitoneal Intraoperative Chemotherapy in the Treatment of Advanced Epithelial Ovarian Cancer. Journal of Oncology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-465613
American Medical Association (AMA)
Tentes, Antonios-Apostolos K.& Kakolyris, Stylianos& Kyziridis, Dimitrios& Karamveri, Christina. Cytoreductive Surgery Combined with Hyperthermic Intraperitoneal Intraoperative Chemotherapy in the Treatment of Advanced Epithelial Ovarian Cancer. Journal of Oncology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-465613
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465613