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Inhalation Induced Stresses and Flow Characteristics in Human Airways through Fluid-Structure Interaction Analysis
Joint Authors
Koombua, Kittisak
Pidaparti, Ramana M.
Source
Modelling and Simulation in Engineering
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-08-04
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Better understanding of stresses and flow characteristics in the human airways is very important for many clinical applications such as aerosol drug therapy, inhalation toxicology, and airway remodeling process.
The bifurcation geometry of airway generations 3 to 5 based on the ICRP tracheobronchial model was chosen to analyze the flow characteristics and stresses during inhalation.
A computational model was developed to investigate the airway tissue flexibility effect on stresses and flow characteristics in the airways.
The finite-element method with the fluid-structure interaction analysis was employed to investigate the transient responses of the flow characteristics and stresses in the airways during inhalation.
The simulation results showed that tissue flexibility affected the maximum airflow velocity, airway pressure, and wall shear stress about 2%, 7%, and 6%, respectively.
The simulation results also showed that the differences between the orthotropic and isotropic material models on the airway stresses were in the ranges of 25–52%.
The results from the present study suggest that it is very important to incorporate the orthotropic tissue properties into a computational model for studying flow characteristics and stresses in the airways.
American Psychological Association (APA)
Koombua, Kittisak& Pidaparti, Ramana M.. 2008. Inhalation Induced Stresses and Flow Characteristics in Human Airways through Fluid-Structure Interaction Analysis. Modelling and Simulation in Engineering،Vol. 2008, no. 2008, pp.1-8.
https://search.emarefa.net/detail/BIM-465651
Modern Language Association (MLA)
Koombua, Kittisak& Pidaparti, Ramana M.. Inhalation Induced Stresses and Flow Characteristics in Human Airways through Fluid-Structure Interaction Analysis. Modelling and Simulation in Engineering No. 2008 (2008), pp.1-8.
https://search.emarefa.net/detail/BIM-465651
American Medical Association (AMA)
Koombua, Kittisak& Pidaparti, Ramana M.. Inhalation Induced Stresses and Flow Characteristics in Human Airways through Fluid-Structure Interaction Analysis. Modelling and Simulation in Engineering. 2008. Vol. 2008, no. 2008, pp.1-8.
https://search.emarefa.net/detail/BIM-465651
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465651