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Predictive Symptoms and Signs of Severe Dengue Disease for Patients with Dengue Fever : A Meta-Analysis
Joint Authors
Zhang, X. H.
Chen, X. G.
Peng, H. J.
Zhou, Y. P.
Zhou, F. Y.
Liu, Z. H.
Zhang, H.
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-07-01
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The aim of the meta-analysis was to provide more solid evidence for the reliability of the new classification.
A systematic literature search was performed using PubMed, Armed Forces Pest Management Board Literature Retrieval System, and Google Scholar up to August 2012.
A pooled odds ratio (OR) was calculated using either a random-effect or a fixed-effect model.
A total of 16 papers were identified.
Among the 11 factors studied, five symptoms demonstrated an increased risk for SDD, including bleeding [OR: 13.617; 95% confidence interval (CI): 3.281, 56.508], vomiting/nausea (OR: 1.692; 95% CI: 1.256, 2.280), abdominal pain (OR: 2.278; 95% CI: 1.631, 3.182), skin rashes (OR: 2.031; 95% CI: 1.269, 3.250), and hepatomegaly (OR: 4.751; 95% CI: 1.769, 12.570).
Among the four bleeding-related symptoms including hematemesis, melena, gum bleeding, and epistaxis, only hematemesis (OR: 6.174; 95% CI: 2.66, 14.334; P<0.001) and melena (OR: 10.351; 95% CI: 3.065, 34.956; P<0.001) were significantly associated with SDD.
No significant associations with SDD were found for gender, lethargy, retroorbital pain, diarrhea, or tourniquet test, whereas headache appeared protective (OR: 0.555; 95% CI: 0.455, 0.676).
The meta-analysis suggests that bleeding (hematemesis/melena), vomiting/nausea, abdominal pain, skin rashes, and hepatomegaly may predict the development of SDD in patients with DF, while headache may predict otherwise.
American Psychological Association (APA)
Zhang, H.& Zhou, Y. P.& Peng, H. J.& Zhang, X. H.& Zhou, F. Y.& Liu, Z. H.…[et al.]. 2014. Predictive Symptoms and Signs of Severe Dengue Disease for Patients with Dengue Fever : A Meta-Analysis. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-465707
Modern Language Association (MLA)
Zhang, H.…[et al.]. Predictive Symptoms and Signs of Severe Dengue Disease for Patients with Dengue Fever : A Meta-Analysis. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-465707
American Medical Association (AMA)
Zhang, H.& Zhou, Y. P.& Peng, H. J.& Zhang, X. H.& Zhou, F. Y.& Liu, Z. H.…[et al.]. Predictive Symptoms and Signs of Severe Dengue Disease for Patients with Dengue Fever : A Meta-Analysis. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-465707
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465707