Fatal Multiorgan Failure Associated with Disseminated Herpes Simplex Virus-1 Infection : A Case Report
Joint Authors
Volk, Thomas
Pokorny, Juliane
Glas, Michael
Smola, Sigrun
Pfuhl, Thorsten
Kamradt, Jörn
Bohle, Rainer M.
Bücker, Arno
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-16
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Herpes simplex virus type 1 (HSV-1) infections cause typical dermal and mucosal lesions in children and adults.
Also complications to the peripheral and central nervous system, pneumonia or hepatitis are well known.
However, dissemination to viscera in adults is rare and predominantly observed in immunocompromised patients.
Here we describe the case of a 70-year-old male admitted with macrohematuria and signs of acute infection and finally deceasing in a septic shock with multi organ failure 17 days after admission to intensive care unit.
No bacterial or fungal infection could be detected during his stay, but only two days before death the patient showed signs of rectal, orolabial and genital herpes infection.
The presence of HSV-1 was detected in swabs taken from the lesions, oropharyngeal fluid as well as in plasma.
Post-mortem polymerase chain reaction analyses confirmed a disseminated infection with HSV-1 involving various organs and tissues but excluding the central nervous system.
Autopsy revealed a predominantly retroperitoneal diffuse large B-cell lymphoma as the suspected origin of immunosuppression underlying herpes simplex dissemination.
American Psychological Association (APA)
Glas, Michael& Smola, Sigrun& Pfuhl, Thorsten& Pokorny, Juliane& Bohle, Rainer M.& Bücker, Arno…[et al.]. 2012. Fatal Multiorgan Failure Associated with Disseminated Herpes Simplex Virus-1 Infection : A Case Report. Case Reports in Critical Care،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-465710
Modern Language Association (MLA)
Glas, Michael…[et al.]. Fatal Multiorgan Failure Associated with Disseminated Herpes Simplex Virus-1 Infection : A Case Report. Case Reports in Critical Care No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-465710
American Medical Association (AMA)
Glas, Michael& Smola, Sigrun& Pfuhl, Thorsten& Pokorny, Juliane& Bohle, Rainer M.& Bücker, Arno…[et al.]. Fatal Multiorgan Failure Associated with Disseminated Herpes Simplex Virus-1 Infection : A Case Report. Case Reports in Critical Care. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-465710
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465710