Genetics of Uveal Melanoma and Cutaneous Melanoma : Two of a Kind?
Joint Authors
de Klein, Annelies
Kilic, Emine
Paridaens, Dion
van den Bosch, Thomas
Source
Dermatology Research and Practice
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-06
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Cutaneous melanoma and uveal melanoma both derive from melanocytes but show remarkable differences in tumorigenesis, mode of metastatic spread, genetic alterations, and therapeutic response.
In this review we discuss the differences and similarities along with the genetic research techniques available and the contribution to our current understanding of melanoma.
The several chromosomal aberrations already identified prove to be very strong predictors of decreased survival in CM and UM patients.
Especially in UM, where the overall risk of metastasis is high (45%), genetic research might aid clinicians in selecting high-risk patients for future systemic adjuvant therapies.
American Psychological Association (APA)
van den Bosch, Thomas& Kilic, Emine& Paridaens, Dion& de Klein, Annelies. 2010. Genetics of Uveal Melanoma and Cutaneous Melanoma : Two of a Kind?. Dermatology Research and Practice،Vol. 2010, no. 2010, pp.1-13.
https://search.emarefa.net/detail/BIM-465771
Modern Language Association (MLA)
van den Bosch, Thomas…[et al.]. Genetics of Uveal Melanoma and Cutaneous Melanoma : Two of a Kind?. Dermatology Research and Practice No. 2010 (2010), pp.1-13.
https://search.emarefa.net/detail/BIM-465771
American Medical Association (AMA)
van den Bosch, Thomas& Kilic, Emine& Paridaens, Dion& de Klein, Annelies. Genetics of Uveal Melanoma and Cutaneous Melanoma : Two of a Kind?. Dermatology Research and Practice. 2010. Vol. 2010, no. 2010, pp.1-13.
https://search.emarefa.net/detail/BIM-465771
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465771
