![](/images/graphics-bg.png)
Biomarkers of Chronic Inflammatory State in Uremia and Cardiovascular Disease
Joint Authors
Migliori, Massimiliano
Scatena, Alessia
Panichi, Vincenzo
Paoletti, Sabrina
Marchetti, Valentina
Beati, Sara
Source
International Journal of Inflammation
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-06-04
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Cardiovascular disease is the leading cause of death in the general population; traditional risk factors seem inadequate to explain completely the remarkable prevalence of cardiovascular mortality and morbidity observed in the uremic population.
A role for chronic inflammation has been well established in the development of atherosclerotic disease, and, on the basis of these observations, atherosclerosis might be considered an inflammatory disease.
Inflammation has been implicated in the etiology of coronary artery disease in the general population, and traditional inflammatory biomarkers such as C-reactive protein (CRP) and interleukin-6 (IL-6) have been shown to predict cardiovascular events in both symptomatic and asymptomatic individuals as well as those in the uremic population.
Later on, new nontraditional markers were related to the risk of cardiovascular morbidity and mortality in general and in uremic population.
As a consequence of the expanding research base and availability of assays, the number of inflammatory marker tests ordered by clinicians for cardiovascular disease (CVD) risk prediction has grown rapidly and several commercial assays have become available.
So, up to now we can consider that several new nontraditional markers as CD40-CD40 ligand system and pentraxin-3 seem to be significant features of cardiovascular disease in general and in ESRD population.
American Psychological Association (APA)
Panichi, Vincenzo& Scatena, Alessia& Migliori, Massimiliano& Marchetti, Valentina& Paoletti, Sabrina& Beati, Sara. 2012. Biomarkers of Chronic Inflammatory State in Uremia and Cardiovascular Disease. International Journal of Inflammation،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-465773
Modern Language Association (MLA)
Panichi, Vincenzo…[et al.]. Biomarkers of Chronic Inflammatory State in Uremia and Cardiovascular Disease. International Journal of Inflammation No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-465773
American Medical Association (AMA)
Panichi, Vincenzo& Scatena, Alessia& Migliori, Massimiliano& Marchetti, Valentina& Paoletti, Sabrina& Beati, Sara. Biomarkers of Chronic Inflammatory State in Uremia and Cardiovascular Disease. International Journal of Inflammation. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-465773
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465773