Synthesis, Antimicrobial, and Anticoagulant Activities of 2-(Arylsulfonyl)indane-1,3-diones
Joint Authors
Ramesh, Penugonda
Jeyachandran, Malaichamy
Source
Organic Chemistry International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-15
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
2-(Arylsulfonyl)indane-1,3-diones, earlier synthesized by Claisen condensation involving diethyl phthalate and aryl methyl sulphones, are found to be potent blood anticoagulants.
In search of improved analogs of 2-(arylsulfonyl)indane-1,3-dione, we have synthesized them (7 a-f) by a different route involving Knoevenagel reaction between phthalic anhydride and arylsulfonylacetates in the presence of pyridine-piperidine medium for the first time.
The synthesized 2-(arylsulfonyl)indane-1,3-diones were evaluated for antimicrobial and anticoagulant activities and all of them registered significant activity.
American Psychological Association (APA)
Jeyachandran, Malaichamy& Ramesh, Penugonda. 2011. Synthesis, Antimicrobial, and Anticoagulant Activities of 2-(Arylsulfonyl)indane-1,3-diones. Organic Chemistry International،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-465835
Modern Language Association (MLA)
Jeyachandran, Malaichamy& Ramesh, Penugonda. Synthesis, Antimicrobial, and Anticoagulant Activities of 2-(Arylsulfonyl)indane-1,3-diones. Organic Chemistry International No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-465835
American Medical Association (AMA)
Jeyachandran, Malaichamy& Ramesh, Penugonda. Synthesis, Antimicrobial, and Anticoagulant Activities of 2-(Arylsulfonyl)indane-1,3-diones. Organic Chemistry International. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-465835
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465835
