The Comparison of the Effects of Sevoflurane Inhalation Anesthesia and Intravenous Propofol Anesthesia on Oxidative Stress in One Lung Ventilation
Joint Authors
Demirci, Yucel
Mentese, Ahmet
Dohman, Davut
Kayir, Selcuk
Erturk, Engin
Beşir, Ahmet
Kutanis, Dilek
Topaloglu, Selma
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-01-09
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Background.
The aim of this study is to compare the effects of sevoflurane and propofol on one lung ventilation (OLV) induced ischemia-reperfusion injury (IRI) by determining the blood gas, ischemia-modified albumin (IMA), and malonyldialdehyde (MDA).
Material and Methods.
Forty-four patients undergoing thoracic surgery with OLV were randomized in two groups (sevoflurane Group S, propofol Group P).
Anesthesia was inducted with thiopental and was maintained with 1–2.5% of sevoflurane within the 40/60% of O2/N2O mixture in Group S.
In Group P anesthesia was inducted with propofol and was maintained with infusion of propofol and remifentanil.
Hemodynamic records and blood samples were obtained before anesthesia induction (t1), 1 min before two lung ventilation (t2), 30 min after two lung ventilation (t3), and postoperative sixth hours (t4).
Results.
Heart rate at t2 and t3 in Group P was significantly lower than that in Group S.
While there were no significant differences in terms of pH and pCO2, pO2 at t2 and t3 in Group S was significantly lower than that in Group P.
IMA levels at t4 in Group S were significantly lower than those in Group P.
Conclusion.
Sevoflurane may offer protection against IRI after OLV in thoracic surgery.
American Psychological Association (APA)
Erturk, Engin& Topaloglu, Selma& Dohman, Davut& Kutanis, Dilek& Beşir, Ahmet& Demirci, Yucel…[et al.]. 2014. The Comparison of the Effects of Sevoflurane Inhalation Anesthesia and Intravenous Propofol Anesthesia on Oxidative Stress in One Lung Ventilation. BioMed Research International،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-465847
Modern Language Association (MLA)
Erturk, Engin…[et al.]. The Comparison of the Effects of Sevoflurane Inhalation Anesthesia and Intravenous Propofol Anesthesia on Oxidative Stress in One Lung Ventilation. BioMed Research International No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-465847
American Medical Association (AMA)
Erturk, Engin& Topaloglu, Selma& Dohman, Davut& Kutanis, Dilek& Beşir, Ahmet& Demirci, Yucel…[et al.]. The Comparison of the Effects of Sevoflurane Inhalation Anesthesia and Intravenous Propofol Anesthesia on Oxidative Stress in One Lung Ventilation. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-465847
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465847