Role of New Biomarkers : Functional and Structural Damage
Joint Authors
Psallida, Vasiliki
Tsigou, Evdoxia
Demponeras, Christos
Boutzouka, Eleni
Baltopoulos, George
Source
Critical Care Research and Practice
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-02-05
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Traditional diagnosis of acute kidney injury (AKI) depends on detection of oliguria and rise of serum creatinine level, which is an unreliable and delayed marker of kidney damage.
Delayed diagnosis of AKI in the critically ill patient is related to increased morbidity and mortality, prolonged length of stay, and cost escalation.
The discovery of a reliable biomarker for early diagnosis of AKI would be very helpful in facilitating early intervention, evaluating the effectiveness of therapy, and eventually reducing cost and improving outcome.
Innovative technologies such as genomics and proteomics have contributed to the discovery of new biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL), cystatin C (Cys C), kidney injury molecule-1 (KIM-1), interleukin-18 (IL-18), and liver-type fatty acid binding protein (L-FABP).
The current status of the most promising of these novel AKI biomarkers, including NGAL, Cys C, KIM-1, L-FABP, and IL-18, is reviewed.
American Psychological Association (APA)
Tsigou, Evdoxia& Psallida, Vasiliki& Demponeras, Christos& Boutzouka, Eleni& Baltopoulos, George. 2013. Role of New Biomarkers : Functional and Structural Damage. Critical Care Research and Practice،Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-465859
Modern Language Association (MLA)
Tsigou, Evdoxia…[et al.]. Role of New Biomarkers : Functional and Structural Damage. Critical Care Research and Practice No. 2013 (2013), pp.1-13.
https://search.emarefa.net/detail/BIM-465859
American Medical Association (AMA)
Tsigou, Evdoxia& Psallida, Vasiliki& Demponeras, Christos& Boutzouka, Eleni& Baltopoulos, George. Role of New Biomarkers : Functional and Structural Damage. Critical Care Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-13.
https://search.emarefa.net/detail/BIM-465859
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465859