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Sentinel Node Mapping for Breast Cancer : Current Situation
Joint Authors
Vidal-Sicart, Sergi
Olmos, Renato Valdés
Source
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-08-15
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Axillary node status is a major prognostic factor in early-stage disease.
Traditional staging needs levels I and II axillary lymph node dissection.
Axillary involvement is found in 10%–30% of patients with T1 (<2 cm) tumours.
Sentinel lymph node biopsy is a minimal invasive method of checking the potential nodal involvement.
It is based on the assumption of an orderly progression of lymph node invasion by metastatic cells from tumour site.
Thus, when sentinel node is free of metastases the remaining nodes are free, too (with a false negative rate lesser than 5%).
Moreover, Randomized trials demonstrated a marked reduction of complications associated with the sentinel lymph node biopsy when compared with axillary lymph node dissection.
Currently, the sentinel node biopsy procedure is recognized as the standard treatment for stages I and II.
In these stages, this approach has a positive node rate similar to those observed after lymphadenectomy, a significant decrease in morbidity and similar nodal relapse rates at 5 years.
In this review, the indications and contraindications of the sentinel node biopsy are summarized and the methodological aspects discussed.
Finally, the new technologic and histologic developments allow to develop a more accurate and refinate technique that can achieve virtually the identification of 100% of sentinel nodes and reduce the false negative rate.
American Psychological Association (APA)
Vidal-Sicart, Sergi& Olmos, Renato Valdés. 2012. Sentinel Node Mapping for Breast Cancer : Current Situation. Journal of Oncology،Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-465879
Modern Language Association (MLA)
Vidal-Sicart, Sergi& Olmos, Renato Valdés. Sentinel Node Mapping for Breast Cancer : Current Situation. Journal of Oncology No. 2012 (2012), pp.1-7.
https://search.emarefa.net/detail/BIM-465879
American Medical Association (AMA)
Vidal-Sicart, Sergi& Olmos, Renato Valdés. Sentinel Node Mapping for Breast Cancer : Current Situation. Journal of Oncology. 2012. Vol. 2012, no. 2012, pp.1-7.
https://search.emarefa.net/detail/BIM-465879
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465879