Tourette Syndrome and Klippel-Feil Anomaly in a Child with Chromosome 22q11 Duplication
Joint Authors
Clarke, Raymond A.
Diwan, Ashish D.
Fang, Zhi Ming
Gilbert, Donald L.
Source
Issue
Vol. 2009, Issue 2009 (31 Dec. 2009), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2009-12-22
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
This is the first case description of the association of Klippel-Feil Syndrome (KFS), Tourette Syndrome (TS), Motor Stereotypies, and Obsessive Compulsive Behavior, with chromosome 22q11.2 Duplication Syndrome (22q11DupS).
Neuropsychiatric symptoms in persons with 22q11.2 deletion, including obsessive compulsiveness, anxiety, hyperactivity, and one prior case report of TS, have been attributed to low copy number effects on Catechol-O-Methyltransferase (COMT).
However, the present unique case of 22q11DupS and TS suggests a more complex relationship involving another gene(s) at or near this locus.
American Psychological Association (APA)
Clarke, Raymond A.& Fang, Zhi Ming& Diwan, Ashish D.& Gilbert, Donald L.. 2009. Tourette Syndrome and Klippel-Feil Anomaly in a Child with Chromosome 22q11 Duplication. Case Reports in Medicine،Vol. 2009, no. 2009, pp.1-5.
https://search.emarefa.net/detail/BIM-465902
Modern Language Association (MLA)
Clarke, Raymond A.…[et al.]. Tourette Syndrome and Klippel-Feil Anomaly in a Child with Chromosome 22q11 Duplication. Case Reports in Medicine No. 2009 (2009), pp.1-5.
https://search.emarefa.net/detail/BIM-465902
American Medical Association (AMA)
Clarke, Raymond A.& Fang, Zhi Ming& Diwan, Ashish D.& Gilbert, Donald L.. Tourette Syndrome and Klippel-Feil Anomaly in a Child with Chromosome 22q11 Duplication. Case Reports in Medicine. 2009. Vol. 2009, no. 2009, pp.1-5.
https://search.emarefa.net/detail/BIM-465902
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-465902
