How Do Cells Make Decisions : Engineering Micro- and Nanoenvironments for Cell Migration
Joint Authors
Ngalim, Siti Hawa
Le Saux, Guillaume
Magenau, Astrid
Gaus, Katharina
Gooding, J. Justin
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-06-23
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Cell migration contributes to cancer metastasis and involves cell adhesion to the extracellular matrix (ECM), force generation through the cell's cytoskeletal, and finally cell detachment.
Both adhesive cues from the ECM and soluble cues from neighbouring cells and tissue trigger intracellular signalling pathways that are essential for cell migration.
While the machinery of many signalling pathways is relatively well understood, how hierarchies of different and conflicting signals are established is a new area of cellular cancer research.
We examine the recent advances in microfabrication, microfluidics, and nanotechnology that can be utilized to engineer micro- and nanoscaled cellular environments.
Controlling both adhesive and soluble cues for migration may allow us to decipher how cells become motile, choose the direction for migration, and how oncogenic transformations influences these decision-making processes.
American Psychological Association (APA)
Ngalim, Siti Hawa& Magenau, Astrid& Le Saux, Guillaume& Gooding, J. Justin& Gaus, Katharina. 2010. How Do Cells Make Decisions : Engineering Micro- and Nanoenvironments for Cell Migration. Journal of Oncology،Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-466049
Modern Language Association (MLA)
Ngalim, Siti Hawa…[et al.]. How Do Cells Make Decisions : Engineering Micro- and Nanoenvironments for Cell Migration. Journal of Oncology No. 2010 (2010), pp.1-7.
https://search.emarefa.net/detail/BIM-466049
American Medical Association (AMA)
Ngalim, Siti Hawa& Magenau, Astrid& Le Saux, Guillaume& Gooding, J. Justin& Gaus, Katharina. How Do Cells Make Decisions : Engineering Micro- and Nanoenvironments for Cell Migration. Journal of Oncology. 2010. Vol. 2010, no. 2010, pp.1-7.
https://search.emarefa.net/detail/BIM-466049
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466049