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Genetic Polymorphism of Cancer Susceptibility Genes and HPV Infection in Cervical Carcinogenesis
Joint Authors
Toji, Eisaku
Okamoto, Yoshiaki
Yamamoto, Michiko
Tanaka, Ichiro
Torii, Kiyo
Ueda, Masatsugu
Noda, Sadamu
Nunobiki, Osamu
Akashi, Kyoko
Izuma, Shinji
Sato, Naomi
Source
Pathology Research International
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-05-31
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
It is widely accepted that specific human papillomavirus (HPV) types are the central etiologic agent of cervical carcinogenesis.
However, a number of infected women do not develop invasive lesions, suggesting that other environmental and host factors may play decisive roles in the persistence of HPV infection and further malignant conversion of cervical epithelium.
Although many previous reports have focused on HPV and environmental factors, the role of host susceptibility to cervical carcinogenesis is largely unknown.
Here, we review the findings of genetic association studies in cervical carcinogenesis with special reference to polymorphisms of glutathione-S-transferase (GST) isoforms, p53 codon 72, murine double-minute 2 homolog (MDM2) gene promoter 309, and FAS gene promoter -670 together with HPV types including our recent research results.
American Psychological Association (APA)
Nunobiki, Osamu& Ueda, Masatsugu& Toji, Eisaku& Yamamoto, Michiko& Akashi, Kyoko& Sato, Naomi…[et al.]. 2011. Genetic Polymorphism of Cancer Susceptibility Genes and HPV Infection in Cervical Carcinogenesis. Pathology Research International،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-466113
Modern Language Association (MLA)
Nunobiki, Osamu…[et al.]. Genetic Polymorphism of Cancer Susceptibility Genes and HPV Infection in Cervical Carcinogenesis. Pathology Research International No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-466113
American Medical Association (AMA)
Nunobiki, Osamu& Ueda, Masatsugu& Toji, Eisaku& Yamamoto, Michiko& Akashi, Kyoko& Sato, Naomi…[et al.]. Genetic Polymorphism of Cancer Susceptibility Genes and HPV Infection in Cervical Carcinogenesis. Pathology Research International. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-466113
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466113