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High-Resolution Optical Imaging of Benign and Malignant Mucosa in the Upper Aerodigestive Tract : An Atlas for Image-Guided Surgery
Joint Authors
Polydorides, Alexandros D.
Anandasabapathy, Sharmila
Sikora, Andrew G.
Park, Richard W.
Gillenwater, Ann M.
Vila, Peter M.
Levy, Lauren L.
Richards-Kortum, Rebecca
Miles, Brett
Gurudutt, Vivek V.
Teng, Marita S.
Genden, Eric M.
Schwarz, Richard
Source
ISRN Minimally Invasive Surgery
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-09-03
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background.
High-resolution optical imaging provides real-time visualization of mucosa in the upper aerodigestive tract (UADT) which allows non-invasive discrimination of benign and neoplastic epithelium.
The high-resolution microendoscope (HRME) utilizes a fiberoptic probe in conjunction with a tissue contrast agent to display nuclei and cellular architecture.
This technology has broad potential applications to intraoperative margin detection and early cancer detection.
Methods.
Our group has created an extensive image collection of both neoplastic and normal epithelium of the UADT.
Here, we present and describe imaging characteristics of benign, dysplastic, and malignant mucosa in the oral cavity, oropharynx, larynx, and esophagus.
Results.
There are differences in the nuclear organization and overall tissue architecture of benign and malignant mucosa which correlate with histopathologic diagnosis.
Different anatomic subsites also display unique imaging characteristics.
Conclusion.
HRME allows discrimination between benign and neoplastic mucosa, and familiarity with the characteristics of each subsite facilitates correct diagnosis.
American Psychological Association (APA)
Levy, Lauren L.& Vila, Peter M.& Park, Richard W.& Schwarz, Richard& Polydorides, Alexandros D.& Teng, Marita S.…[et al.]. 2012. High-Resolution Optical Imaging of Benign and Malignant Mucosa in the Upper Aerodigestive Tract : An Atlas for Image-Guided Surgery. ISRN Minimally Invasive Surgery،Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-466137
Modern Language Association (MLA)
Levy, Lauren L.…[et al.]. High-Resolution Optical Imaging of Benign and Malignant Mucosa in the Upper Aerodigestive Tract : An Atlas for Image-Guided Surgery. ISRN Minimally Invasive Surgery No. 2012 (2012), pp.1-9.
https://search.emarefa.net/detail/BIM-466137
American Medical Association (AMA)
Levy, Lauren L.& Vila, Peter M.& Park, Richard W.& Schwarz, Richard& Polydorides, Alexandros D.& Teng, Marita S.…[et al.]. High-Resolution Optical Imaging of Benign and Malignant Mucosa in the Upper Aerodigestive Tract : An Atlas for Image-Guided Surgery. ISRN Minimally Invasive Surgery. 2012. Vol. 2012, no. 2012, pp.1-9.
https://search.emarefa.net/detail/BIM-466137
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466137