Successful Treatment of Mild Pediatric Kasabach-Merritt Phenomenon with Propranolol Monotherapy
Joint Authors
Charoenkwan, Pimlak
Choeyprasert, Worawut
Natesirinilkul, Rungrote
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-05-22
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Kasabach-Merritt phenomenon (KMP) is relatively rare in childhood and adolescents with high mortality rate because of its hemorrhagic complications and unresponsiveness to treatments such as corticosteroids, vincristine, intravascular embolization, and/or surgery.
Propranolol, a β-adrenergic receptor blocker, has a promising efficacy against vascular tumors such as infantile hemangiomas.
But limited and variable data has been reported regarding the role of propranolol in treatment of KMP.
We herein reported the successful treatment of mild pediatric KMP with propranolol monotherapy in a case of a five-week-old child with kaposiform hemangioendothelioma with successful treatment of both clinical and hematologic responses.
After eight months of follow-up, patient still had stable cutaneous lesion while receiving propranolol monotherapy.
Regular hematologic monitoring was done in order to detect any late relapse of the disease.
Six months after discontinuation of propranolol, patient has still remained free of hematologic relapse, and primary cutaneous lesion has become a pale pink, 1 cm sized skin lesion.
American Psychological Association (APA)
Choeyprasert, Worawut& Natesirinilkul, Rungrote& Charoenkwan, Pimlak. 2014. Successful Treatment of Mild Pediatric Kasabach-Merritt Phenomenon with Propranolol Monotherapy. Case Reports in Hematology،Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-466171
Modern Language Association (MLA)
Choeyprasert, Worawut…[et al.]. Successful Treatment of Mild Pediatric Kasabach-Merritt Phenomenon with Propranolol Monotherapy. Case Reports in Hematology No. 2014 (2014), pp.1-4.
https://search.emarefa.net/detail/BIM-466171
American Medical Association (AMA)
Choeyprasert, Worawut& Natesirinilkul, Rungrote& Charoenkwan, Pimlak. Successful Treatment of Mild Pediatric Kasabach-Merritt Phenomenon with Propranolol Monotherapy. Case Reports in Hematology. 2014. Vol. 2014, no. 2014, pp.1-4.
https://search.emarefa.net/detail/BIM-466171
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466171