Is Subcellular Localization Informative for Modeling Protein-Protein Interaction Signal?
Joint Authors
Yu, Weichuan
Shih, Weichung Joe
Luo, Dajie
Zhao, Hongyu
Tan, Jun
Liu, Junfeng
Harner, E. James
Source
Research Letters in Signal Processing
Issue
Vol. 2008, Issue 2008 (31 Dec. 2008), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2008-02-28
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Statistical methods have been intensively applied in genomic signal processing (Dougherty et al.
2005).
For budding yeast Saccharomyces cerevisiae with around 6000 proteins, genome-wide protein-protein-interaction (PPI) (Fromont-Racine et al.
2000, Ito et al.
2001, Newman et al.
2000, and Uetz et al.
2000 among others) and protein subcellular localization (PSL) (Huh et al.
2003) data recently became available and for the latter the presence of 4152 proteins is experimentally tested in each of the 22 subcellular compartments.
Recent work shows that multiple biological sources are helpful for both PSL and PPI predictions, and this paper studies statistical feasibility of modeling PPI from PSL since PSLs may play different marginal or joint roles in the complex regulatory network.
However, our results indicate that PSL may be controversial for this purpose as an independent source.
American Psychological Association (APA)
Liu, Junfeng& Zhao, Hongyu& Tan, Jun& Luo, Dajie& Yu, Weichuan& Harner, E. James…[et al.]. 2008. Is Subcellular Localization Informative for Modeling Protein-Protein Interaction Signal?. Research Letters in Signal Processing،Vol. 2008, no. 2008, pp.1-5.
https://search.emarefa.net/detail/BIM-466223
Modern Language Association (MLA)
Liu, Junfeng…[et al.]. Is Subcellular Localization Informative for Modeling Protein-Protein Interaction Signal?. Research Letters in Signal Processing No. 2008 (2008), pp.1-5.
https://search.emarefa.net/detail/BIM-466223
American Medical Association (AMA)
Liu, Junfeng& Zhao, Hongyu& Tan, Jun& Luo, Dajie& Yu, Weichuan& Harner, E. James…[et al.]. Is Subcellular Localization Informative for Modeling Protein-Protein Interaction Signal?. Research Letters in Signal Processing. 2008. Vol. 2008, no. 2008, pp.1-5.
https://search.emarefa.net/detail/BIM-466223
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466223