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ArnicaHydroxyethyl Salicylate Combination Spray for Ankle Distortion : A Four-Arm Randomised Double-Blind Study
Joint Authors
Kučera, Alexander
Barna, Milos
Kučera, Miroslav
Hladiková, Marie
Kolar, Pavel
Source
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-03-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
570 patients with acute ankle joint distortion were randomized to four treatment groups: a combination spray of arnica tincture and hydroxyethyl salicylate (HES; group A, n=228), arnica (B, n=57), HES (C, n=228), and placebo (D, n=57).
The medication was applied 4-5 times daily for 10 days.
Efficacy was assessed on day 3-4 by evaluating pain on motion on a visual analogue scale (VAS).
Pain improvement in group A was significantly superior over groups B–D (t-test with unadjusted baseline values, P<4×10−7 and ANCOVA after adjustment, P<5×10−11) and approximately corresponded to the cumulative effect of the single constituents (12.1, 7.5, and 18.7 mm VAS for A versus B, A versus C, and A versus D; 95% CI 8.0–16.2, 4.7–10.4, and 14.8–22.5 mm).
The combination is justified by the additive effects of the single active constituents.
American Psychological Association (APA)
Kučera, Miroslav& Kolar, Pavel& Barna, Milos& Kučera, Alexander& Hladiková, Marie. 2011. ArnicaHydroxyethyl Salicylate Combination Spray for Ankle Distortion : A Four-Arm Randomised Double-Blind Study. Pain Research and Treatment،Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-466271
Modern Language Association (MLA)
Kučera, Miroslav…[et al.]. ArnicaHydroxyethyl Salicylate Combination Spray for Ankle Distortion : A Four-Arm Randomised Double-Blind Study. Pain Research and Treatment No. 2011 (2011), pp.1-7.
https://search.emarefa.net/detail/BIM-466271
American Medical Association (AMA)
Kučera, Miroslav& Kolar, Pavel& Barna, Milos& Kučera, Alexander& Hladiková, Marie. ArnicaHydroxyethyl Salicylate Combination Spray for Ankle Distortion : A Four-Arm Randomised Double-Blind Study. Pain Research and Treatment. 2011. Vol. 2011, no. 2011, pp.1-7.
https://search.emarefa.net/detail/BIM-466271
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466271