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Assessment of the Vitamin B12 Status of Pregnant Women in Nigeria Using Plasma Holotranscobalamin
Joint Authors
Ikeh, Eugene I.
Crossey, Michael J.
Glew, Robert H.
Pam, Victor
VanderJagt, Dorothy J.
Bryant, Jessica
Ujah, Innocent A. O.
Hilgart, Amelia
Source
ISRN Obstetrics and Gynecology
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-14
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Maternal vitamin B12 deficiency during pregnancy is an independent risk factor for neural tube defects and other neurological problems in infants.
We determined the vitamin B12 status of 143 pregnant women in Nigeria representing all trimesters who presented to an antenatal clinic in Jos, Nigeria, using holotranscobalamin II levels (holoTCII), which is a measure of the vitamin B12 that is available for uptake into tissues.
The holoTCII concentration ranged from 13 to 128 pmol/L.
Using a cutoff of 40 pmol/L, 36% of the women were classified as vitamin B12-deficient.
HoloTCII concentrations correlated negatively with plasma homocysteine levels (r=−0.24, P =0.003) and positively with red blood cell folate concentrations (r=0.28, P<0.001).
These data underscore the importance of supplementing pregnant women in Nigeria with vitamin B12 in order to ensure adequate vitamin B12 status and decrease the risk for neural tube defects.
American Psychological Association (APA)
VanderJagt, Dorothy J.& Ujah, Innocent A. O.& Ikeh, Eugene I.& Bryant, Jessica& Pam, Victor& Hilgart, Amelia…[et al.]. 2011. Assessment of the Vitamin B12 Status of Pregnant Women in Nigeria Using Plasma Holotranscobalamin. ISRN Obstetrics and Gynecology،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-466296
Modern Language Association (MLA)
VanderJagt, Dorothy J.…[et al.]. Assessment of the Vitamin B12 Status of Pregnant Women in Nigeria Using Plasma Holotranscobalamin. ISRN Obstetrics and Gynecology No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-466296
American Medical Association (AMA)
VanderJagt, Dorothy J.& Ujah, Innocent A. O.& Ikeh, Eugene I.& Bryant, Jessica& Pam, Victor& Hilgart, Amelia…[et al.]. Assessment of the Vitamin B12 Status of Pregnant Women in Nigeria Using Plasma Holotranscobalamin. ISRN Obstetrics and Gynecology. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-466296
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466296