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Diffuse Leukoencephalopathy and Subacute Parkinsonism as an Early Manifestation of Systemic Lupus Erythematosus
Joint Authors
Tse, Gary G.
McMurtray, Aaron M.
Nakamoto, Beau K.
Chow, Dominic C.
Santos-Ocampo, Alberto S.
Source
Case Reports in Neurological Medicine
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-11-28
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Parkinsonism in SLE is rare.
Diffuse leukoencephalopathy is equally uncommon and is associated with a poor prognosis.
We present a single case of a 50-year-old Filipino man who presented with a generalized discoid rash after starting lisinopril.
The rash persisted despite discontinuation of lisinopril, and over the next three months, he developed rapidly progressive parkinsonism.
Brain MRI showed symmetric confluent T2-hyperintensities involving the white matter and basal ganglia.
Four of the 11 American College of Rheumatology criteria for the classification of SLE were met.
A rheumatologist made a diagnosis of SLE with cutaneous and central nervous system involvement.
Significant neurologic and radiologic improvement occurred following treatment with IV steroids followed by a prolonged taper.
This report highlights a case of subacute parkinsonism with a diffuse leukoencephalopathy as an early manifestation of SLE which resulted in a good recovery following treatment with only immunosuppressive therapy.
American Psychological Association (APA)
Tse, Gary G.& Santos-Ocampo, Alberto S.& Chow, Dominic C.& McMurtray, Aaron M.& Nakamoto, Beau K.. 2013. Diffuse Leukoencephalopathy and Subacute Parkinsonism as an Early Manifestation of Systemic Lupus Erythematosus. Case Reports in Neurological Medicine،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-466330
Modern Language Association (MLA)
Tse, Gary G.…[et al.]. Diffuse Leukoencephalopathy and Subacute Parkinsonism as an Early Manifestation of Systemic Lupus Erythematosus. Case Reports in Neurological Medicine No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-466330
American Medical Association (AMA)
Tse, Gary G.& Santos-Ocampo, Alberto S.& Chow, Dominic C.& McMurtray, Aaron M.& Nakamoto, Beau K.. Diffuse Leukoencephalopathy and Subacute Parkinsonism as an Early Manifestation of Systemic Lupus Erythematosus. Case Reports in Neurological Medicine. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-466330
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466330