
Clonazepam as Agonist Substitution Treatment for Benzodiazepine Dependence : A Case Report
Joint Authors
Pacini, Matteo
Dell'Osso, Liliana
Rugani, Fabio
Bacciardi, Silvia
Maremmani, Icro
Maremmani, Angelo Giovanni Icro
Rovai, Luca
Source
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-01-30
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Nowadays, the misuse of benzodiazepines (BZDs) is a cause for a serious concern among pharmacologically inexperienced patients, whether treated or untreated, that could lead to significant complications, including tolerance, dependence, and addiction.
We present a case report in which an Italian patient affected by anxiety disorder and treated with BZDs presented a severe case of dependence on BZDs.
We treated him according to an agonist substitution approach, switching from the abused BZD to a slow-onset, long-acting, high potency agonist (clonazepam), and looking at the methadone treatment model as paradigm.
We decided to use clonazepam for its pharmacokinetic properties.
The advantage of choosing a slow-onset, long-lasting BZD for the treatment of our patient was that it led us to a remarkable improvement in the clinical situation, including the cessation of craving, absence of withdrawal symptoms, reduced anxiety, improvements in social functioning, and a better cognition level.
American Psychological Association (APA)
Maremmani, Angelo Giovanni Icro& Rovai, Luca& Rugani, Fabio& Bacciardi, Silvia& Pacini, Matteo& Dell'Osso, Liliana…[et al.]. 2013. Clonazepam as Agonist Substitution Treatment for Benzodiazepine Dependence : A Case Report. Case Reports in Psychiatry،Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-466377
Modern Language Association (MLA)
Maremmani, Angelo Giovanni Icro…[et al.]. Clonazepam as Agonist Substitution Treatment for Benzodiazepine Dependence : A Case Report. Case Reports in Psychiatry No. 2013 (2013), pp.1-4.
https://search.emarefa.net/detail/BIM-466377
American Medical Association (AMA)
Maremmani, Angelo Giovanni Icro& Rovai, Luca& Rugani, Fabio& Bacciardi, Silvia& Pacini, Matteo& Dell'Osso, Liliana…[et al.]. Clonazepam as Agonist Substitution Treatment for Benzodiazepine Dependence : A Case Report. Case Reports in Psychiatry. 2013. Vol. 2013, no. 2013, pp.1-4.
https://search.emarefa.net/detail/BIM-466377
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466377