Functional Food Targeting the Regulation of Obesity-Induced Inflammatory Responses and Pathologies
Joint Authors
Kawada, Teruo
Yu, Rina
Lin, Shan
Hirai, Shizuka
Goto, Tsuyoshi
Uemura, Taku
Takahashi, Nobuyuki
Source
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-05-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Obesity is associated with a low-grade systemic chronic inflammatory state, characterized by the abnormal production of pro- and anti-inflammatory adipocytokines.
It has been found that immune cells such as macrophages can infiltrate adipose tissue and are responsible for the majority of inflammatory cytokine production.
Obesity-induced inflammation is considered a potential mechanism linking obesity to its related pathologies, such as insulin resistance, cardiovascular diseases, type-2 diabetes, and some immune disorders.
Therefore, targeting obesity-related inflammatory components may be a useful strategy to prevent or ameliorate the development of such obesity-related diseases.
It has been shown that several food components can modulate inflammatory responses in adipose tissue via various mechanisms, some of which are dependent on peroxisome proliferator-activated receptor γ (PPARγ), whereas others are independent on PPARγ, by attenuating signals of nuclear factor-κB (NF-κB) and/or c-Jun amino-terminal kinase (JNK).
In this review, we introduce the beneficial effects of anti-inflammatory phytochemicals that can help prevent obesity-induced inflammatory responses and pathologies.
American Psychological Association (APA)
Hirai, Shizuka& Takahashi, Nobuyuki& Goto, Tsuyoshi& Lin, Shan& Uemura, Taku& Yu, Rina…[et al.]. 2010. Functional Food Targeting the Regulation of Obesity-Induced Inflammatory Responses and Pathologies. Mediators of Inflammation،Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-466390
Modern Language Association (MLA)
Hirai, Shizuka…[et al.]. Functional Food Targeting the Regulation of Obesity-Induced Inflammatory Responses and Pathologies. Mediators of Inflammation No. 2010 (2010), pp.1-8.
https://search.emarefa.net/detail/BIM-466390
American Medical Association (AMA)
Hirai, Shizuka& Takahashi, Nobuyuki& Goto, Tsuyoshi& Lin, Shan& Uemura, Taku& Yu, Rina…[et al.]. Functional Food Targeting the Regulation of Obesity-Induced Inflammatory Responses and Pathologies. Mediators of Inflammation. 2010. Vol. 2010, no. 2010, pp.1-8.
https://search.emarefa.net/detail/BIM-466390
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466390