Adsorptive Cathodic Stripping Voltammetric Determination of Cefoperazone in Bulk Powder, Pharmaceutical Dosage Forms, and Human Urine
Joint Authors
Phuc, Phan Hong
Huyen, Dao Thi
Hoang, Vu Dang
Source
Journal of Analytical Methods in Chemistry
Issue
Vol. 2013, Issue 2013 (31 Dec. 2013), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2013-09-10
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The electroreduction behaviour and determination of cefoperazone using a hanging mercury drop electrode were investigated.
Cyclic voltammograms of cefoperazone recorded in universal Britton-Robinson buffers pH 3–6 exhibited a single irreversible cathodic peak.
The process was adsorption-controlled.
Britton-Robinson buffer 0.04 M pH 4.0 was selected as a supporting electrolyte for quantitative purposes by differential pulse and square wave adsorptive cathodic stripping voltammetry.
The experimental voltammetric conditions were optimized using Central Composite Face design.
A reduction wave was seen in the range from −0.7 to −0.8 V.
These voltammetric techniques were successfully validated as per ICH guidelines and applied for the determination of cefoperazone in its single and sulbactam containing powders for injection and statistically comparable to USP-HPLC.
They were further extended to determine cefoperazone in spiked human urine with no matrix effect.
American Psychological Association (APA)
Hoang, Vu Dang& Huyen, Dao Thi& Phuc, Phan Hong. 2013. Adsorptive Cathodic Stripping Voltammetric Determination of Cefoperazone in Bulk Powder, Pharmaceutical Dosage Forms, and Human Urine. Journal of Analytical Methods in Chemistry،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-466400
Modern Language Association (MLA)
Hoang, Vu Dang…[et al.]. Adsorptive Cathodic Stripping Voltammetric Determination of Cefoperazone in Bulk Powder, Pharmaceutical Dosage Forms, and Human Urine. Journal of Analytical Methods in Chemistry No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-466400
American Medical Association (AMA)
Hoang, Vu Dang& Huyen, Dao Thi& Phuc, Phan Hong. Adsorptive Cathodic Stripping Voltammetric Determination of Cefoperazone in Bulk Powder, Pharmaceutical Dosage Forms, and Human Urine. Journal of Analytical Methods in Chemistry. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-466400
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466400