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Neuroimaging in Animal Seizure Models with 18FDG-PET
Joint Authors
Tsirka, Stella E.
Mirrione, Martine M.
Source
Epilepsy Research and Treatment
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-07
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Small animal neuroimaging has become increasingly available to researchers, expanding the breadth of questions studied with these methods.
Applying these noninvasive techniques to the open questions underlying epileptogenesis is no exception.
A major advantage of small animal neuroimaging is its translational appeal.
Studies can be well controlled and manipulated, examining the living brain in the animal before, during, and after the disease onset or disease treatment.
The results can also be compared to data collected on human patients.
Over the past decade, we and others have explored metabolic patterns in animal models of epilepsy to gain insight into the circuitry underlying development of the disease.
In this paper, we provide technical details on how metabolic imaging that uses 2-deoxy-2[18F]fluoro-D-glucose (18FDG) and positron emission tomography (PET) is performed and explain the strengths and limitations of these studies.
We will also highlight recent advances toward understanding epileptogenesis through small animal imaging.
American Psychological Association (APA)
Mirrione, Martine M.& Tsirka, Stella E.. 2011. Neuroimaging in Animal Seizure Models with 18FDG-PET. Epilepsy Research and Treatment،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-466540
Modern Language Association (MLA)
Mirrione, Martine M.& Tsirka, Stella E.. Neuroimaging in Animal Seizure Models with 18FDG-PET. Epilepsy Research and Treatment No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-466540
American Medical Association (AMA)
Mirrione, Martine M.& Tsirka, Stella E.. Neuroimaging in Animal Seizure Models with 18FDG-PET. Epilepsy Research and Treatment. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-466540
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466540