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Role of Translationally Controlled Tumor Protein in Cancer Progression
Joint Authors
Guan, Xin-Yuan
Chen, Leilei
Chan, Tim Hon Man
Source
Biochemistry Research International
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-04-17
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Translationally controlled tumor protein (TCTP) is a highly conserved and ubiquitously expressed protein in all eukaryotes—highlighting its important functions in the cell.
Previous studies revealed that TCTP is implicated in many biological processes, including cell growth, tumor reversion, and induction of pluripotent stem cell.
A recent study on the solution structure from fission yeast orthologue classifies TCTP under a family of small chaperone proteins.
There is growing evidence in the literature that TCTP is a multifunctional protein and exerts its biological activity at the extracellular and intracellular levels.
Although TCTP is not a tumor-specific protein, our research group, among several others, focused on the role(s) of TCTP in cancer progression.
In this paper, we will summarize the current scientific knowledge of TCTP in different aspects, and the precise oncogenic mechanisms of TCTP will be discussed in detail.
American Psychological Association (APA)
Chan, Tim Hon Man& Chen, Leilei& Guan, Xin-Yuan. 2012. Role of Translationally Controlled Tumor Protein in Cancer Progression. Biochemistry Research International،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-466554
Modern Language Association (MLA)
Chan, Tim Hon Man…[et al.]. Role of Translationally Controlled Tumor Protein in Cancer Progression. Biochemistry Research International No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-466554
American Medical Association (AMA)
Chan, Tim Hon Man& Chen, Leilei& Guan, Xin-Yuan. Role of Translationally Controlled Tumor Protein in Cancer Progression. Biochemistry Research International. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-466554
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466554