The Tumor Necrosis Factor Superfamily of Cytokines in the Inflammatory Myopathies : Potential Targets for Therapy
Joint Authors
Creus, Kim K.
De Paepe, Boel
De Bleecker, Jan L.
Source
Clinical and Developmental Immunology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-10-23
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The idiopathic inflammatory myopathies (IM) represent a heterogeneous group of autoimmune diseases, of which dermatomyositis (DM), polymyositis (PM), and sporadic inclusion body myositis (IBM) are the most common.
The crucial role played by tumor necrosis factor alpha (TNFα) in the IM has long been recognized.
However, so far, 18 other members of the TNF superfamily have been characterized, and many of these have not yet received the attention they deserve.
In this paper, we summarize current findings for all TNF cytokines in IM, pinpointing what we know already and where current knowledge fails.
For each TNF family member, possibilities for treating inflammatory diseases in general and the IM in particular are explored.
American Psychological Association (APA)
De Paepe, Boel& Creus, Kim K.& De Bleecker, Jan L.. 2011. The Tumor Necrosis Factor Superfamily of Cytokines in the Inflammatory Myopathies : Potential Targets for Therapy. Clinical and Developmental Immunology،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-466560
Modern Language Association (MLA)
De Paepe, Boel…[et al.]. The Tumor Necrosis Factor Superfamily of Cytokines in the Inflammatory Myopathies : Potential Targets for Therapy. Clinical and Developmental Immunology No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-466560
American Medical Association (AMA)
De Paepe, Boel& Creus, Kim K.& De Bleecker, Jan L.. The Tumor Necrosis Factor Superfamily of Cytokines in the Inflammatory Myopathies : Potential Targets for Therapy. Clinical and Developmental Immunology. 2011. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-466560
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466560