Risk of Orthopedic Surgical Site Infections in Patients with Rheumatoid Arthritis Treated with Antitumor Necrosis Factor Alfa Therapy
Joint Authors
Maria Henrique da Mota, Licia
dos Santos-Neto, Leopoldo Luiz
da Cunha, Bernardo Matos
Source
International Journal of Rheumatology
Issue
Vol. 2012, Issue 2012 (31 Dec. 2012), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2012-02-23
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
International guidelines recommend interruption of anti-TNF medications in the perioperative period, but there are no randomized trials to support such recommendation.
Objectives.
To study literature evidence assessing the risk of surgical site infections in orthopedic surgery patients with RA using anti-TNF drugs, compared to untreated patients or those using conventional DMARD.
Methods.
Systematic review of cohort studies is concerning surgical site infections in orthopedic procedures in patients with RA.
Results.
Three studies were selected.
Only one was considered of high-quality, albeit with low statistical power.
The review resulted in inconclusive data, since the best quality study showed no significant differences between groups, while others showed increased risk of infections in patients using anti-TNF medications.
Conclusion.
It is unclear whether patients with RA using anti-TNF medications are at increased risk of surgical site infections.
Randomized controlled trials or new high quality observational studies are needed to clarify the issue.
American Psychological Association (APA)
da Cunha, Bernardo Matos& Maria Henrique da Mota, Licia& dos Santos-Neto, Leopoldo Luiz. 2012. Risk of Orthopedic Surgical Site Infections in Patients with Rheumatoid Arthritis Treated with Antitumor Necrosis Factor Alfa Therapy. International Journal of Rheumatology،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-466576
Modern Language Association (MLA)
da Cunha, Bernardo Matos…[et al.]. Risk of Orthopedic Surgical Site Infections in Patients with Rheumatoid Arthritis Treated with Antitumor Necrosis Factor Alfa Therapy. International Journal of Rheumatology No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-466576
American Medical Association (AMA)
da Cunha, Bernardo Matos& Maria Henrique da Mota, Licia& dos Santos-Neto, Leopoldo Luiz. Risk of Orthopedic Surgical Site Infections in Patients with Rheumatoid Arthritis Treated with Antitumor Necrosis Factor Alfa Therapy. International Journal of Rheumatology. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-466576
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466576