Evasion of Apoptosis as a Cellular Stress Response in Cancer
Author
Source
International Journal of Cell Biology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-02-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
One of the hallmarks of human cancers is the intrinsic or acquired resistance to apoptosis.
Evasion of apoptosis can be part of a cellular stress response to ensure the cell's survival upon exposure to stressful stimuli.
Apoptosis resistance may contribute to carcinogenesis, tumor progression, and also treatment resistance, since most current anticancer therapies including chemotherapy as well as radio- and immunotherapies primarily act by activating cell death pathways including apoptosis in cancer cells.
Hence, a better understanding of the molecular mechanisms regarding how cellular stress stimuli trigger antiapoptotic mechanisms and how this contributes to tumor resistance to apoptotic cell death is expected to provide the basis for a rational approach to overcome apoptosis resistance mechanisms in cancers.
American Psychological Association (APA)
Fulda, Simone. 2010. Evasion of Apoptosis as a Cellular Stress Response in Cancer. International Journal of Cell Biology،Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-466701
Modern Language Association (MLA)
Fulda, Simone. Evasion of Apoptosis as a Cellular Stress Response in Cancer. International Journal of Cell Biology No. 2010 (2010), pp.1-6.
https://search.emarefa.net/detail/BIM-466701
American Medical Association (AMA)
Fulda, Simone. Evasion of Apoptosis as a Cellular Stress Response in Cancer. International Journal of Cell Biology. 2010. Vol. 2010, no. 2010, pp.1-6.
https://search.emarefa.net/detail/BIM-466701
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466701