Identifying Gastric Cancer Related Genes Using the Shortest Path Algorithm and Protein-Protein Interaction Network
Joint Authors
Jiang, Yang
Ren, Hui
Shu, Yang
Shi, Ying
Yuan, Fei
Li, Li-Peng
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-03-05
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Gastric cancer, as one of the leading causes of cancer related deaths worldwide, causes about 800,000 deaths per year.
Up to now, the mechanism underlying this disease is still not totally uncovered.
Identification of related genes of this disease is an important step which can help to understand the mechanism underlying this disease, thereby designing effective treatments.
In this study, some novel gastric cancer related genes were discovered based on the knowledge of known gastric cancer related ones.
These genes were searched by applying the shortest path algorithm in protein-protein interaction network.
The analysis results suggest that some of them are indeed involved in the biological process of gastric cancer, which indicates that they are the actual gastric cancer related genes with high probability.
It is hopeful that the findings in this study may help promote the study of this disease and the methods can provide new insights to study various diseases.
American Psychological Association (APA)
Jiang, Yang& Shu, Yang& Shi, Ying& Li, Li-Peng& Yuan, Fei& Ren, Hui. 2014. Identifying Gastric Cancer Related Genes Using the Shortest Path Algorithm and Protein-Protein Interaction Network. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-466751
Modern Language Association (MLA)
Jiang, Yang…[et al.]. Identifying Gastric Cancer Related Genes Using the Shortest Path Algorithm and Protein-Protein Interaction Network. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-466751
American Medical Association (AMA)
Jiang, Yang& Shu, Yang& Shi, Ying& Li, Li-Peng& Yuan, Fei& Ren, Hui. Identifying Gastric Cancer Related Genes Using the Shortest Path Algorithm and Protein-Protein Interaction Network. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-466751
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466751