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Evaluation of Novel Tools to Facilitate the Detection and Characterization of Leprosy Patients in China
Joint Authors
Yan, Wen
Yuan, Lian-Chao
Zhang, Ying
You, Yuan Gang
Duthie, Malcolm S.
Li, Huan-Ying
Yuan, You Hua
Source
Issue
Vol. 2014, Issue 2014 (31 Dec. 2014), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2014-08-12
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Leprosy is the disabling outcome of chronic infection with Mycobacterium leprae.
The disease often evades early detection, particularly now that fewer clinicians are able to confidently diagnose the disease following the integration of leprosy control measures within general health services in many countries.
Although leprosy is officially eliminated in China, endemic regions remain in some difficult-to-reach, underdeveloped areas in Southwest China.
In order to better understand the extent of M.
leprae infection and identify new leprosy cases in a timely manner, simple tools that can detect infection and the early disease are required.
In this report we evaluated the performance of antigen-specific ELISA, the NDO-LID rapid diagnostic test, and antigen-specific whole blood assays (WBA) as potential diagnostic tools.
Our data support the use of antibody detection tests and WBA to facilitate the diagnosis of multibacillary and paucibacillary leprosy, respectively.
These tools could be invaluable for increased, but simplified, monitoring of individuals in order to provide referrals for clinical exam and early leprosy diagnosis.
American Psychological Association (APA)
Yan, Wen& You, Yuan Gang& Yuan, Lian-Chao& Yuan, You Hua& Zhang, Ying& Duthie, Malcolm S.…[et al.]. 2014. Evaluation of Novel Tools to Facilitate the Detection and Characterization of Leprosy Patients in China. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-466799
Modern Language Association (MLA)
Yan, Wen…[et al.]. Evaluation of Novel Tools to Facilitate the Detection and Characterization of Leprosy Patients in China. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-466799
American Medical Association (AMA)
Yan, Wen& You, Yuan Gang& Yuan, Lian-Chao& Yuan, You Hua& Zhang, Ying& Duthie, Malcolm S.…[et al.]. Evaluation of Novel Tools to Facilitate the Detection and Characterization of Leprosy Patients in China. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-466799
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466799