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High-Sensitivity C-Reactive Protein : An Independent Risk Factor for Left Ventricular Hypertrophy in Patients with Lupus Nephritis
Joint Authors
Zhang, Minfang
Yu, Zanzhe
Shi, Beili
Ni, Zhaohui
Wang, Qin
Qian, Jiaqi
Yan, Yucheng
Cai, Hong
Mou, Shan
Cao, Liou
Source
Journal of Biomedicine and Biotechnology
Issue
Vol. 2010, Issue 2010 (31 Dec. 2010), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2010-11-07
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Objective.
To determine the prevalence of left ventricular hypertrophy (LVH) and its associated risk factors in lupus nephritis (LN) patients.
Methods.
287 LN patients (age: 38.54 ± 13.31, 262 female) were recruited.
Echocardiography and serum high-sensitivity C-reactive protein (hs-CRP) were measured.
Their relationship was evaluated by univariate correlation analysis and multivariate regression analysis.
Results.
The prevalence of LVH in this cohort was 21.25% (n=61).
Serum hs-CRP level was significantly elevated in patients with LVH compared to those without (8.03 (3.22–30.95) versus 3.93 (1.48–9.48) mg/L, P<.01), and correlated with left ventricular mass index (LVMI) (r=0.314, P=.001).
Multivariate regression analysis further confirmed that hs-CRP was an independent risk factor (β=0.338, P=.002) for LVH in patients with LN.
Conclusions.
Our findings demonstrated that serum hs-CRP level is independently correlated with LVMI and suggested that measurement of hs-CRP may provide important clinical information to investigate LVH in LN patients.
American Psychological Association (APA)
Shi, Beili& Ni, Zhaohui& Cai, Hong& Zhang, Minfang& Mou, Shan& Wang, Qin…[et al.]. 2010. High-Sensitivity C-Reactive Protein : An Independent Risk Factor for Left Ventricular Hypertrophy in Patients with Lupus Nephritis. Journal of Biomedicine and Biotechnology،Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-466922
Modern Language Association (MLA)
Shi, Beili…[et al.]. High-Sensitivity C-Reactive Protein : An Independent Risk Factor for Left Ventricular Hypertrophy in Patients with Lupus Nephritis. Journal of Biomedicine and Biotechnology No. 2010 (2010), pp.1-5.
https://search.emarefa.net/detail/BIM-466922
American Medical Association (AMA)
Shi, Beili& Ni, Zhaohui& Cai, Hong& Zhang, Minfang& Mou, Shan& Wang, Qin…[et al.]. High-Sensitivity C-Reactive Protein : An Independent Risk Factor for Left Ventricular Hypertrophy in Patients with Lupus Nephritis. Journal of Biomedicine and Biotechnology. 2010. Vol. 2010, no. 2010, pp.1-5.
https://search.emarefa.net/detail/BIM-466922
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466922