Single-Walled-Carbon-Nanotube-Modified Pyrolytic Graphite Electrode Used as a Simple Sensor for the Determination of Salbutamol in Urine

Joint Authors

Goyal, Rajendra N.
Bishnoi, Sunita
Agrawal, Bharati

Source

International Journal of Electrochemistry

Issue

Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2011-02-07

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Chemistry

Abstract EN

A fast and sensitive voltammetric method has been proposed for the determination of salbutamol at single-walled-carbon-nanotube-modified edge-plane pyrolytic graphite electrode (SWNT/EPPGE) in human urine.

The electrochemical response of salbutamol was determined by square wave voltammetry (SWV) in phosphate buffer solution (PBS) at physiological pH 7.2.

The modified electrode showed improved voltammetric response towards the oxidation of salbutamol, and a well-defined anodic peak was observed at ∼600 mV with enhanced peak current in comparison to the bare electrode.

Linear calibration plot using SWNT/EPPGE was obtained in the concentration range of 50 to 2500 ngml-1 with sensitivity and detection limit of 2.15 nA/ngml-1 and 4.31 ngml-1, respectively.

The developed method has been successfully applied for the determination of salbutamol in commercial preparations and human body fluids.

Fast analysis of salbutamol in human urine makes the proposed method of great interest for doping control purposes at the site of competitive games.

American Psychological Association (APA)

Goyal, Rajendra N.& Bishnoi, Sunita& Agrawal, Bharati. 2011. Single-Walled-Carbon-Nanotube-Modified Pyrolytic Graphite Electrode Used as a Simple Sensor for the Determination of Salbutamol in Urine. International Journal of Electrochemistry،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-466930

Modern Language Association (MLA)

Goyal, Rajendra N.…[et al.]. Single-Walled-Carbon-Nanotube-Modified Pyrolytic Graphite Electrode Used as a Simple Sensor for the Determination of Salbutamol in Urine. International Journal of Electrochemistry No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-466930

American Medical Association (AMA)

Goyal, Rajendra N.& Bishnoi, Sunita& Agrawal, Bharati. Single-Walled-Carbon-Nanotube-Modified Pyrolytic Graphite Electrode Used as a Simple Sensor for the Determination of Salbutamol in Urine. International Journal of Electrochemistry. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-466930

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-466930