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The Role of Proteomics in the Diagnosis and Treatment of Women's Cancers : Current Trends in Technology and Future Opportunities
Joint Authors
Breuer, Eun-Kyoung Yim
Murph, Mandi M.
Source
International Journal of Proteomics
Issue
Vol. 2011, Issue 2011 (31 Dec. 2011), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2011-07-25
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Natural & Life Sciences (Multidisciplinary)
Biology
Abstract EN
Technological and scientific innovations over the last decade have greatly contributed to improved diagnostics, predictive models, and prognosis among cancers affecting women.
In fact, an explosion of information in these areas has almost assured future generations that outcomes in cancer will continue to improve.
Herein we discuss the current status of breast, cervical, and ovarian cancers as it relates to screening, disease diagnosis, and treatment options.
Among the differences in these cancers, it is striking that breast cancer has multiple predictive tests based upon tumor biomarkers and sophisticated, individualized options for prescription therapeutics while ovarian cancer lacks these tools.
In addition, cervical cancer leads the way in innovative, cancer-preventative vaccines and multiple screening options to prevent disease progression.
For each of these malignancies, emerging proteomic technologies based upon mass spectrometry, stable isotope labeling with amino acids, high-throughput ELISA, tissue or protein microarray techniques, and click chemistry in the pursuit of activity-based profiling can pioneer the next generation of discovery.
We will discuss six of the latest techniques to understand proteomics in cancer and highlight research utilizing these techniques with the goal of improvement in the management of women's cancers.
American Psychological Association (APA)
Breuer, Eun-Kyoung Yim& Murph, Mandi M.. 2011. The Role of Proteomics in the Diagnosis and Treatment of Women's Cancers : Current Trends in Technology and Future Opportunities. International Journal of Proteomics،Vol. 2011, no. 2011, pp.1-17.
https://search.emarefa.net/detail/BIM-466939
Modern Language Association (MLA)
Breuer, Eun-Kyoung Yim& Murph, Mandi M.. The Role of Proteomics in the Diagnosis and Treatment of Women's Cancers : Current Trends in Technology and Future Opportunities. International Journal of Proteomics No. 2011 (2011), pp.1-17.
https://search.emarefa.net/detail/BIM-466939
American Medical Association (AMA)
Breuer, Eun-Kyoung Yim& Murph, Mandi M.. The Role of Proteomics in the Diagnosis and Treatment of Women's Cancers : Current Trends in Technology and Future Opportunities. International Journal of Proteomics. 2011. Vol. 2011, no. 2011, pp.1-17.
https://search.emarefa.net/detail/BIM-466939
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-466939